Ontology highlight
ABSTRACT:
SUBMITTER: Anderson SM
PROVIDER: S-EPMC7602985 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Nutrients 20201017 10
While vitamin D insufficiency is known to impact a multitude of health outcomes, including HIV-1, little is known about the role of vitamin D-mediated immune regulation in the female reproductive tract (FRT). We performed a pilot clinical study of 20 women with circulating 25(OH)D levels <62.5 nmol/L. Participants were randomized into either weekly or daily high-dose oral vitamin D supplementation groups. In addition to serum vitamin D levels, genital mucosal endpoints, including soluble mediato ...[more]