Ontology highlight
ABSTRACT:
SUBMITTER: Santiago RP
PROVIDER: S-EPMC7603616 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Santiago Rayra P RP Figueiredo Camylla V B CVB Fiuza Luciana M LM Yahouédéhou Sètondji C M A SCMA Oliveira Rodrigo M RM Aleluia Milena M MM Carvalho Suellen P SP Fonseca Cleverson A CA Nascimento Valma M L VML Rocha Larissa C LC Guarda Caroline C CC Gonçalves Marilda S MS
Mediators of inflammation 20201013
Individuals with sickle cell disease (SCD) present both chronic and acute inflammatory events. The TGF-<i>β</i> pathway is known to play a role in immune response, angiogenesis, inflammation, hematopoiesis, vascular inflammation, and cell proliferation. Polymorphisms in the transforming growth factor-beta receptor 3 (<i>TGFBR3</i>) gene have been linked to several inflammatory diseases. This study investigated associations between two <i>TGFBR3</i> haplotypes and classical laboratory parameters, ...[more]