Ontology highlight
ABSTRACT:
SUBMITTER: Bayik D
PROVIDER: S-EPMC7606602 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Bayik Defne D Lauko Adam J AJ Roversi Gustavo A GA Serbinowski Emily E Acevedo-Moreno Lou-Anne LA Lanigan Christopher C Orujov Mushfig M Lo Alice A Alban Tyler J TJ Kim Adam A Silver Daniel J DJ Nagy Laura E LE Brown J Mark JM Allende Daniela S DS Aucejo Federico N FN Lathia Justin D JD
Scientific reports 20201102 1
Myeloid-derived suppressor cells (MDSCs) are immunosuppressive cells that are increased in patients with numerous malignancies including viral-derived hepatocellular carcinoma (HCC). Here, we report an elevation of MDSCs in the peripheral blood of patients with other hepatobiliary malignancies including non-viral HCC, neuroendocrine tumors (NET), and colorectal carcinoma with liver metastases (CRLM), but not cholangiocarcinoma (CCA). The investigation of myeloid cell infiltration in HCC, NET and ...[more]