Rapidly declining body temperature in a tropical human population.
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ABSTRACT:
SUBMITTER: Gurven M
PROVIDER: S-EPMC7608783 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Publications
Rapidly declining body temperature in a tropical human population.
Gurven Michael M Kraft Thomas S TS Alami Sarah S Adrian Juan Copajira JC Linares Edhitt Cortez EC Cummings Daniel D Rodriguez Daniel Eid DE Hooper Paul L PL Jaeggi Adrian V AV Gutierrez Raul Quispe RQ Suarez Ivan Maldonado IM Seabright Edmond E Kaplan Hillard H Stieglitz Jonathan J Trumble Benjamin B
Science advances 20201028 44
Normal human body temperature (BT) has long been considered to be 37.0°C. Yet, BTs have declined over the past two centuries in the United States, coinciding with reductions in infection and increasing life expectancy. The generality of and reasons behind this phenomenon have not yet been well studied. Here, we show that Bolivian forager-farmers (<i>n</i> = 17,958 observations of 5481 adults age 15+ years) inhabiting a pathogen-rich environment exhibited higher BT when first examined in the earl ...[more]
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Control Intervention1: Passive Hypothermia Before HIPEC: As per our standard anesthesia protocol, warming devices will be stopped 1 hour before the HIPEC phase to maintain temperature between 34.5-35.0 degree C.
Primary outcome(s): Proportion of patients who have achieved normal body temperature of at least 35 degree C post HIPECTimepoint: Immediately (0 hour) after shifting the patients to ICU or postanaesthesia care unit.
Study Design: Randomized, Parallel Group Trial Method of generating randomization sequence:Computer generated randomization Method of allocation concealment:On-site computer system Blinding and masking:Open Label
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