A prospective study of the association between rate of nicotine metabolism and alcohol use in tobacco users in the United States.

ABSTRACT:

Background

Rate of nicotine metabolism has been identified as a biochemical risk factor for nicotine use and dependence; however, its role in alcohol consumption and related outcomes is not well understood. The current research examined nicotine metabolism rate as a risk factor for alcohol use among current tobacco users. We also examined sex differences in these associations.

Method

Data were taken from Waves 1 and 2 of the Population Assessment of Tobacco and Health (PATH) study, a national longitudinal study of tobacco use and associated health outcomes. The nicotine metabolite ratio (NMR) was calculated as the ratio of trans-3' hydroxycotinine to cotinine in urine samples provided at wave 1. Alcohol use outcomes included past 30-day NIAAA-defined hazardous drinking statu

SUBMITTER: Roberts W 

PROVIDER: S-EPMC7609495 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature