Association of Maternal Prepregnancy Body Mass Index With Fetal Growth and Neonatal Thalamic Brain Connectivity Among Adolescent and Young Women.

ABSTRACT:

Importance

Higher maternal prepregnancy body mass index (BMI; calculated as weight in kilograms divided by height in meters squared) is associated with adverse long-term outcomes for offspring, including obesity, poorer cognitive and social abilities, and increased risk of psychiatric disorders. Less clear is whether higher maternal BMI disrupts fetal growth and brain development.

Objective

To investigate the association of maternal prepregnancy BMI with fetal growth and neonatal functional connectivity.

Design, setting, and participants

This prospective longitudinal cohort study was conducted from 2012 to 2017. Participants included nulliparous pregnant adolescent and young adult women, aged 14 to 19 years who were recruited in the second trimester through Columbia U

SUBMITTER: Spann MN 

PROVIDER: S-EPMC7610195 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature