Programmable icosahedral shell system for virus trapping.
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ABSTRACT:
SUBMITTER: Sigl C
PROVIDER: S-EPMC7611604 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature
Publications
Programmable icosahedral shell system for virus trapping.
Sigl Christian C Willner Elena M EM Engelen Wouter W Kretzmann Jessica A JA Sachenbacher Ken K Liedl Anna A Kolbe Fenna F Wilsch Florian F Aghvami S Ali SA Protzer Ulrike U Hagan Michael F MF Fraden Seth S Dietz Hendrik H
Nature materials 20210614 9
Broad-spectrum antiviral platforms that can decrease or inhibit viral infection would alleviate many threats to global public health. Nonetheless, effective technologies of this kind are still not available. Here, we describe a programmable icosahedral canvas for the self-assembly of icosahedral shells that have viral trapping and antiviral properties. Programmable triangular building blocks constructed from DNA assemble with high yield into various shell objects with user-defined geometries and ...[more]
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