Dataset Information

High-quality brain perfusion SPECT images may be achieved with a high-speed recording using 360° CZT camera.

ABSTRACT:

Objective

The aim of this study was to compare brain perfusion SPECT obtained from a 360° CZT and a conventional Anger camera.

Methods

The 360° CZT camera utilizing a brain configuration, with 12 detectors surrounding the head, was compared to a 2-head Anger camera for count sensitivity and image quality on 30-min SPECT recordings from a brain phantom and from ^99mTc-HMPAO brain perfusion in 2 groups of 21 patients investigated with the CZT and Anger cameras, respectively. Image reconstruction was adjusted according to image contrast for each camera.

Results

The CZT camera provided more than 2-fold increase in count sensitivity, as compared with the Anger camera, as well as (1) lower sharpness indexes, giving evidence of higher spatial resolution, for both peripheral/central brain structures, with respective median values of 5.2%/3.7% versus 2.4%/1.9% for CZT and Anger camera respectively in patients (p < 0.01), and 8.0%/6.9% versus 6.2%/3.7% on phantom; and (2) higher gray/white matter contrast on peripheral/central structures, with respective ratio median values of 1.56/1.35 versus 1.11/1.20 for CZT and Anger camera respectively in patients (p < 0.05), and 2.57/2.17 versus 1.40/1.12 on phantom; and (3) no change in noise level. Image quality, scored visually by experienced physicians, was also significantly higher on CZT than on the Anger camera (+ 80%, p < 0.01), and all these results were unchanged on the CZT images obtained with only a 15?min recording time.

Conclusion

The 360° CZT camera provides brain perfusion images of much higher quality than a conventional Anger camera, even with high-speed recordings, thus demonstrating the potential for repositioning brain perfusion SPECT to the forefront of brain imaging.

SUBMITTER: Bordonne M

PROVIDER: S-EPMC7642149 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Publications

High-quality brain perfusion SPECT images may be achieved with a high-speed recording using 360° CZT camera.

Bordonne Manon M Chawki Mohammad B MB Marie Pierre-Yves PY Zaragori Timothée T Roch Véronique V Grignon Rachel R Imbert Laetitia L Verger Antoine A

EJNMMI physics 20201104 1

<h4>Objective</h4>The aim of this study was to compare brain perfusion SPECT obtained from a 360° CZT and a conventional Anger camera.<h4>Methods</h4>The 360° CZT camera utilizing a brain configuration, with 12 detectors surrounding the head, was compared to a 2-head Anger camera for count sensitivity and image quality on 30-min SPECT recordings from a brain phantom and from <sup>99m</sup>Tc-HMPAO brain perfusion in 2 groups of 21 patients investigated with the CZT and Anger cameras, respectivel ...[more]

PMID: 33146804

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Dataset Information

High-quality brain perfusion SPECT images may be achieved with a high-speed recording using 360° CZT camera.

Objective

Methods

Results

Conclusion

Publications

High-quality brain perfusion SPECT images may be achieved with a high-speed recording using 360° CZT camera.

Similar Datasets

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