Ontology highlight
ABSTRACT:
SUBMITTER: Mu T
PROVIDER: S-EPMC7642341 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Mu Tianhao T Xu Liqin L Zhong Yu Y Liu Xinyu X Zhao Zhikun Z Huang Chaoben C Lan Xiaofeng X Lufei Chengchen C Zhou Yi Y Su Yixun Y Xu Luang L Jiang Miaomiao M Zhou Hongpo H Lin Xinxin X Wu Liang L Peng Siqi S Liu Shiping S Brix Susanne S Dean Michael M Dunn Norris R NR Zaret Kenneth S KS Fu Xin-Yuan XY Hou Yong Y
Communications biology 20201103 1
The liver and gallbladder are among the most important internal organs derived from the endoderm, yet the development of the liver and gallbladder in the early embryonic stages is not fully understood. Using a transgenic Foxa2<sup>eGFP</sup> reporter mouse line, we performed single-cell full-length mRNA sequencing on endodermal and hepatic cells isolated from ten embryonic stages, ranging from E7.5 to E15.5. We identified the embryonic liver developmental trajectory from gut endoderm to hepatobl ...[more]