Dataset Information

Accurate reconstructions of pelvic defects and discontinuities using statistical shape models.

ABSTRACT: Treatment of large acetabular defects and discontinuities remains challenging and relies on the accurate restoration of the native anatomy of the patient. This study introduces and validates a statistical shape model for the reconstruction of acetabular discontinuities with severe bone loss through a two-sided Markov Chain Monte Carlo reconstruction method. The performance of the reconstruction algorithm was evaluated using leave-one-out cross-validation in three defect types with varying severity as well as severe defects with discontinuities. The two-sided reconstruction method was compared to a one-sided methodology. Although, reconstruction errors increased with defect size and this increase was most pronounced for pelvic discontinuities, the two-sided reconstruction method was able to reconstruct the native anatomy with higher accuracy than the one-sided reconstruction method. These findings can improve the preoperative planning and custom implant design in patients with large pelvic defects, both with and without discontinuities.

SUBMITTER: Meynen A

PROVIDER: S-EPMC7643466 | biostudies-literature | 2020 Oct

REPOSITORIES: biostudies-literature

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Accurate reconstructions of pelvic defects and discontinuities using statistical shape models.

Meynen Alexander A Matthews Harold H Nauwelaers Nele N Claes Peter P Mulier Michiel M Scheys Lennart L

Computer methods in biomechanics and biomedical engineering 20200703 13

Treatment of large acetabular defects and discontinuities remains challenging and relies on the accurate restoration of the native anatomy of the patient. This study introduces and validates a statistical shape model for the reconstruction of acetabular discontinuities with severe bone loss through a two-sided Markov Chain Monte Carlo reconstruction method. The performance of the reconstruction algorithm was evaluated using leave-one-out cross-validation in three defect types with varying severi ...[more]

PMID: 32619099

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Project description:Background/objectiveArtificial bone models (ABMs) are used in orthopaedics for research of biomechanics, development of implants and educational purposes. Most of the commercially available ABMs approximate the morphology of Europeans, but they may not depict the Asian anatomy. Therefore, our aim was to develop the first Asian ABM of the pelvis and compare it with the existing pelvic ABM (Synbone®; Caucasian male).MethodsOne hundred clinical computed tomography (CTs) of adult pelvises (male n = 50, female n = 50) of Malay, Chinese and Indian descent were acquired. CTs were segmented and defined landmarks were placed. Three 3D statistical pelvic model and mean models (overall, male, female) were generated. Anatomical variations were analysed using principal component analysis. To measure gender-related differences and differences to the existing ABM, distances between the anterior superior iliac spines (ASIS), the anterior inferior iliac spines (AIIS), the promontory and the symphysis (conjugate vera, CV) as well as the ischial spines (diameter transversa, DT) were quantified.ResultsPrincipal component analysis displayed large variability regarding the pelvic shape and size. Female and male statistical models were similar in ASIS (225 ± 20; 227 ± 13 mm; P = 0.4153) and AIIS (185 ± 11; 187 ± 10 mm; P = 0.3982) and differed in CV (116 ± 10; 105 ± 10 mm; P < 0.0001) and DT (105 ± 7; 88 ± 8 mm; P < 0.0001). Comparing the unisex mean model with the pre-existing ABM, the ASIS (226; 275 mm; P < 0.0001), the AIIS (186; 209 mm; P < 0.0001) and the CV (111; 105 mm; P < 0.0001) differed significantly. Both models were similar regarding DT (97; 95 mm; P = 0.6927). The analysis revealed notable gender- and size-dependent anatomical variations within the Asian population. Chinese, Malay and Indian descents did not differ notably. The overall Asian model was smaller than the existing ABM.The translation potential of this articleOwing to the large differences between the Asian ABM and the pre-existing ABM, as well as differences between genders, the use of an Asian- and gender-specific ABM is important to consider in research, biomechanics and implant development for this population.

Dataset Information

Accurate reconstructions of pelvic defects and discontinuities using statistical shape models.

Publications

Accurate reconstructions of pelvic defects and discontinuities using statistical shape models.

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