Ontology highlight
ABSTRACT:
SUBMITTER: Hepowit NL
PROVIDER: S-EPMC7647399 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
eLife 20201019
Ubiquitination regulates many different cellular processes, including protein quality control, membrane trafficking, and stress responses. The diversity of ubiquitin functions in the cell is partly due to its ability to form chains with distinct linkages that can alter the fate of substrate proteins in unique ways. The complexity of the ubiquitin code is further enhanced by post-translational modifications on ubiquitin itself, the biological functions of which are not well understood. Here, we p ...[more]