Ontology highlight
ABSTRACT:
SUBMITTER: Scher N
PROVIDER: S-EPMC7649452 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Biotechnology reports (Amsterdam, Netherlands) 20201028
<h4>Purpose</h4>Clinical evidence of the radiation-enhancing effects of nanoparticles has emerged.<h4>Materials and methods</h4>We searched the literature in English and French on PubMed up to October 2019. The search term was "nanoparticle" AND "radiotherapy", yielding 1270 results.<h4>Results</h4>The two main NP used in clinical trials were hafnium oxide and gadolinium involving a total of 229 patients. Hafnium oxide NP were used in three phase 1/2 trials on sarcoma, head and neck squamous cel ...[more]