Ontology highlight
ABSTRACT:
SUBMITTER: Jing H
PROVIDER: S-EPMC7649632 | biostudies-literature | 2021 Jan
REPOSITORIES: biostudies-literature
Jing Hongwu H Ackerman William E WE Zhao Guomao G El Helou Yara Y Buhimschi Catalin S CS Buhimschi Irina A IA
Placenta 20201109
We conducted a protein-protein interaction (PPI) network study searching for proteins relevant to pregnancy-associated COVID-19 in pregnancy complicated with severe preeclampsia (sPE) and intra-amniotic infection and/or inflammation (Triple-I). PPI networks from sPE and Triple-I were intersected with the PPI network from coronavirus infection. Common proteins included the SARS-CoV-2 entry receptor ACE2 and ENDOU, a placental endoribonuclease homologous to Nsp15, a protein produced by the virus t ...[more]