Ontology highlight
ABSTRACT:
SUBMITTER: Poe AJ
PROVIDER: S-EPMC7650592 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Poe Adam J AJ Kulkarni Mangesh M Leszczynska Aleksandra A Tang Jie J Shah Ruchi R Jami-Alahmadi Yasaman Y Wang Jason J Kramerov Andrei A AA Wohlschlegel James J Punj Vasu V Ljubimov Alexander V AV Saghizadeh Mehrnoosh M
Cells 20200926 10
MiR-146a is upregulated in the stem cell-enriched limbal region vs. central human cornea and can mediate corneal epithelial wound healing. The aim of this study was to identify miR-146a targets in human primary limbal epithelial cells (LECs) using genomic and proteomic analyses. RNA-seq combined with quantitative proteomics based on multiplexed isobaric tandem mass tag labeling was performed in LECs transfected with miR-146a mimic vs. mimic control. Western blot and immunostaining were used to c ...[more]