Ontology highlight
ABSTRACT:
SUBMITTER: Capone E
PROVIDER: S-EPMC7650653 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Capone Emily E Lamolinara Alessia A Pastorino Fabio F Gentile Roberta R Ponziani Sara S Di Vittorio Giulia G D'Agostino Daniela D Bibbò Sandra S Rossi Cosmo C Piccolo Enza E Iacobelli Valentina V Lattanzio Rossano R Panella Valeria V Sallese Michele M De Laurenzi Vincenzo V Giansanti Francesco F Sala Arturo A Iezzi Manuela M Ponzoni Mirco M Ippoliti Rodolfo R Iacobelli Stefano S Sala Gianluca G
Cancers 20201015 10
Neuroblastoma is the most common extra-cranial solid tumor in infants and children, which accounts for approximately 15% of all cancer-related deaths in the pediatric population. New therapeutic modalities are urgently needed. Antibody-Drug Conjugates (ADC)s-based therapy has been proposed as potential strategy to treat this pediatric malignancy. LGALS3BP is a highly glycosylated protein involved in tumor growth and progression. Studies have shown that LGALS3BP is enriched in extracellular vesic ...[more]