Ontology highlight
ABSTRACT:
SUBMITTER: Serin I
PROVIDER: S-EPMC7653211 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Serin Istemi I Pehlivan Sacide S Gundes Ilknur I Fidan Oyaci Yasemin Y Pehlivan Mustafa M
Annals of hematology 20201110 2
Multiple myeloma (MM) is a disease caused by malignant plasma cells, causing free light chain release accompanying the increase in monoclonal immunoglobulin. Cytochrome P450 (CYP) is one of the large and functional enzyme families composed of various hemoproteins. This protein network has been shown to play a role in many treatment steps in current practices. We aimed to investigate the relationship between genotypes of CYP3A4*1B and treatment response and prognosis of MM. Seventy-two patients d ...[more]