Ontology highlight
ABSTRACT:
SUBMITTER: Ossola P
PROVIDER: S-EPMC7655098 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Ossola Paolo P Garrett Neil N Sharot Tali T Marchesi Carlo C
eLife 20201110
Bipolar disorder is a chronic relapsing condition in which mood episodes are interspersed with periods of wellbeing (euthymia). Shorter periods of euthymia are associated with poorer functioning, so it is crucial to identify predictors of relapse to facilitate treatment. Here, we test the hypothesis that specific valence-dependent learning patterns emerge prior to the clinical manifestation of a relapse, predicting its timing. The ability to update beliefs in response to positive and negative in ...[more]