Discovery and Biosynthesis of Clostyrylpyrones from the Obligate Anaerobe Clostridium roseum.
Ontology highlight
ABSTRACT: Anaerobic bacteria are a promising new source for natural product discovery. Examination of extracts from the obligate anaerobe Clostridium roseum led to the discovery of a new family of natural products, the clostyrylpyrones. The polyketide synthase-based biosynthetic mechanism of clostyrylpyrones is further proposed on the basis of bioinformatic, gene knockout, biochemical analysis, and heterologous expression studies.
SUBMITTER: Li JS
PROVIDER: S-EPMC7655672 | biostudies-literature |
REPOSITORIES: biostudies-literature
ACCESS DATA