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HPLC-assisted automated oligosaccharide synthesis: the implementation of the two-way split valve as a mode of complete automation.


ABSTRACT: Reported herein is the development of a user-friendly platform for simple and transformative automation based on standard HPLC equipment. We showcase how the improved platform works in application to the completely automated, a "press of the button," synthesis of various glycan sequences.

SUBMITTER: Panza M 

PROVIDER: S-EPMC7656230 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature

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HPLC-assisted automated oligosaccharide synthesis: the implementation of the two-way split valve as a mode of complete automation.

Panza Matteo M   Stine Keith J KJ   Demchenko Alexei V AV  

Chemical communications (Cambridge, England) 20200113 9


Reported herein is the development of a user-friendly platform for simple and transformative automation based on standard HPLC equipment. We showcase how the improved platform works in application to the completely automated, a "press of the button," synthesis of various glycan sequences. ...[more]

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