Ontology highlight
ABSTRACT:
SUBMITTER: Herrera M
PROVIDER: S-EPMC7657228 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Herrera Mercedes M Herrera Alberto A Domínguez Gemma G Silva Javier J García Vanesa V García José M JM Gómez Irene I Soldevilla Beatriz B Muñoz Concepción C Provencio Mariano M Campos-Martin Yolanda Y García de Herreros Antonio A Casal Ignacio I Bonilla Félix F Peña Cristina C
Cancer science 20130221 4
Tumor epithelial cells within a tumor coexist with a complex microenvironment in which a variety of interactions between its various components determine the behavior of the primary tumors. Cancer-associated fibroblasts (CAF) and M2 macrophages, characterized by high expression of different markers, including α-SMA, FSP1 and FAP, or CD163 and DCSIGN, respectively, are involved in the malignancy of different tumors. In the present study, expression of the above markers in CAF and M2 macrophages w ...[more]