Ontology highlight
ABSTRACT:
SUBMITTER: Hwang I
PROVIDER: S-EPMC7686699 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Hwang Ilseon I Kim Jeong Won JW Ylaya Kris K Chung Eun Joo EJ Kitano Haruhisa H Perry Candice C Hanaoka Jun J Fukuoka Junya J Chung Joon-Yong JY Hewitt Stephen M SM
Journal of translational medicine 20201123 1
<h4>Background</h4>The tumor microenvironment (TME) is a critical player in tumor progression, metastasis and therapy outcomes. Tumor-associated macrophages (TAMs) are a well-recognized core element of the TME and generally characterized as M2-like macrophages. TAMs are believed to contribute to tumor progression, but the mechanism behind this remains unclear. We aimed to investigate the clinical, angiogenic, and lymphangiogenic significance of TAMs in non-small cell lung cancer (NSCLC).<h4>Meth ...[more]