A Silver Lining.
Ontology highlight
ABSTRACT:
SUBMITTER: Cornell CN
PROVIDER: S-EPMC7659420 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Publications
A Silver Lining.
HSS journal : the musculoskeletal journal of Hospital for Special Surgery 20201112 Suppl 2
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Project description: Not available
| S-EPMC8788139 | biostudies-literature
Project description:COVID-19 has led to an unprecedented reduction in demand for energy for transportation and electricity, a crash in prices and employment in the fossil fuel industries and record-breaking reductions in global carbon emissions. This paper discusses whether this "demand destruction" could spell the beginning of the end for fossil fuels or a temporary recession and the imperative to recover from the current crisis by "building back better" and not the same as before. There are encouraging signs for the renewable energy industry that could make COVID-19 a cloud with a silver lining; whether this is the case will depend not only on the technological realities and social response to the crisis but also on political will and foresight.
| S-EPMC7675242 | biostudies-literature
Project description:Recent studies conclude that the global coronavirus (COVID-19) pandemic decreased power sector CO2 emissions globally and in the United States. In this paper, we analyze the statistical significance of CO2 emissions reductions in the U.S. power sector from March through December 2020. We use Gaussian process (GP) regression to assess whether CO2 emissions reductions would have occurred with reasonable probability in the absence of COVID-19 considering uncertainty due to factors unrelated to the pandemic and adjusting for weather, seasonality, and recent emissions trends. We find that monthly CO2 emissions reductions are only statistically significant in April and May 2020 considering hypothesis tests at 5% significance levels. Separately, we consider the potential impact of COVID-19 on coal-fired power plant retirements through 2022. We find that only a small percentage of U.S. coal power plants are at risk of retirement due to a possible COVID-19-related sustained reduction in electricity demand and prices. We observe and anticipate a return to pre-COVID-19 CO2 emissions in the U.S. power sector.
| S-EPMC8333368 | biostudies-literature
Project description: Not available
| S-EPMC10500972 | biostudies-literature
Project description:The impact of COVID-19 restrictions on human and vehicular mobility on the number of roadkills of wild mammals, and roe deer in particular, was assessed in Lithuania. We statistically analyzed the distribution of all mammals and roe deer (Capreolus capreolus) as the most abundant species annually from 2002 to 2022 and monthly from 2020 to 2021, including during the two restriction periods. Notably, there was a marked decrease in roadkill incidents on main, national and regional roads, particularly in April-May 2020 (the beginning of lockdown period I) and November-December 2020 (the beginning of lockdown period II), 5.1-20.8% and 33.6-54.4%, respectively. During these months, collisions with mammals on the A14 main road were reduced by 75-90%. However, there was a significant increase in the number of roadkills in urban areas, resulting in the total number of mammal-vehicle and roe deer-vehicle collisions in 2020 and 2021 being higher than expected based on long-term trends. However, after restrictions were eased, collision numbers with wildlife on the main, national and regional roads increased again and became higher than expected.
| S-EPMC10525093 | biostudies-literature
Project description:BackgroundHealth-seeking behaviors change during pandemics and may increase with regard to illnesses with symptoms similar to the pandemic. The global reaction to COVID-19 may drive interest in vaccines for other diseases.ObjectivesOur study investigated the correlation between global online interest in COVID-19 and interest in CDC-recommended routine vaccines.Design, settings, measurementsThis infodemiology study used Google Trends data to quantify worldwide interest in COVID-19 and CDC-recommended vaccines using the unit search volume index (SVI), which estimates volume of online search activity relative to highest volume of searches within a specified period. SVIs from December 30, 2019 to March 30, 2020 were collected for "coronavirus (Virus)" and compared with SVIs of search terms related to CDC-recommended adult vaccines. To account for seasonal variation, we compared SVIs from December 30, 2019 to March 30, 2020 with SVIs from the same months in 2015 to 2019. We performed country-level analyses in ten COVID-19 hotspots and ten countries with low disease burden.ResultsThere were significant positive correlations between SVIs for "coronavirus (Virus)" and search terms for pneumococcal (R = 0.89, p < 0.0001) and influenza vaccines (R = 0.93, p < 0.0001) in 2020, which were greater than SVIs for the same terms in 2015-2019 (p = 0.005, p < 0.0001, respectively). Eight in ten COVID-19 hotspots demonstrated significant positive correlations between SVIs for coronavirus and search terms for pneumococcal and influenza vaccines.LimitationsSVIs estimate relative changes in online interest and do not represent the interest of people with no Internet access.ConclusionA peak in worldwide interest in pneumococcal and influenza vaccines coincided with the COVID-19 pandemic in February and March 2020. Trends are likely not seasonal in origin and may be driven by COVID-19 hotspots. Global events may change public perception about the importance of vaccines. Our findings may herald higher demand for pneumonia and influenza vaccines in the upcoming season.
| S-EPMC7315971 | biostudies-literature
Project description:Current environmental and climate changes are having a pronounced influence on the outcome of plant-pathogen interactions, further highlighting the fact that abiotic stresses strongly affect biotic interactions at various levels. For instance, physiological parameters such as plant architecture and tissue organization together with primary and specialized metabolism are affected by environmental constraints, and these combine to make an individual plant either a more or less suitable host for a given pathogen. In addition, abiotic stresses can affect the timely expression of plant defense and pathogen virulence. Indeed, several studies have shown that variations in temperature, and in water and mineral nutrient availability affect the expression of plant defense genes. The expression of virulence genes, known to be crucial for disease outbreak, is also affected by environmental conditions, potentially modifying existing pathosystems and paving the way for emerging pathogens. In this review, we summarize our current knowledge on the impact of abiotic stress on biotic interactions at the transcriptional level in both the plant and the pathogen side of the interaction. We also perform a metadata analysis of four different combinations of abiotic and biotic stresses, which identifies 197 common modulated genes with strong enrichment in Gene Ontology terms related to defense . We also describe the multistress-specific responses of selected defense-related genes.
| S-EPMC7904152 | biostudies-literature
Project description:PurposeThe coronavirus disease 2019 (COVID-19) pandemic has propelled health care workers to the front lines against the pandemic. In addition to anxiety related to infection risks, trainees have the additional burden of learning and career planning while providing care in an uncertain and rapidly changing environment. We conducted a survey to evaluate the practical and psychosocial impact on radiation oncology fellows during the first month of the pandemic.Methods and materialsA 4-part survey was designed and distributed to the fellows in our program. The survey was designed to evaluate the impact of the pandemic on scope of activity and well-being ("Impact on You") and to identify key lessons learned and social factors ("About You") using Likert scales and open-ended response options. The survey included items from the Oldenburg Burnout questionnaire.ResultsA total of 17 participants (71%) responded to the survey. Although there was a significant reduction in the mean time spent on in-person clinics (13.5 h/wk [pre-COVID] vs 9.3 h/wk [3 weeks into the COVID emergency response]; P = .002), this was replaced by virtual consults and other COVID-related activities. The proportion of respondents demonstrating features of burnout in the domains of "disengagement" and "exhaustion" was 71% and 64%, respectively. However, there was also evidence of resilience, with 47% respondents "feeling energized." Top "concerns" and "negative changes" identified related to learning, infection risk and safety, patient care, coping, and concerns about their home country. Top "positive changes" highlighted include work culture, appreciation for leadership caring for the team, the insistence on evidence to guide change, and the implementation of virtual health care.ConclusionsNegative impact needs to be anticipated, acknowledged, and managed. We anticipate understanding the positives that have emerged under these extraordinary circumstances is the "silver lining" of the pandemic, giving us tools and the best leverage to plan for the future.
| S-EPMC7377812 | biostudies-literature
Project description:Pancreatic cancer remains one of the most lethal malignant diseases worldwide. The majority of patients present with advanced disease and, therefore, need palliative chemotherapy. Some chemotherapeutic regimens have been well established as first-line therapies and have been shown to increase survival; however, almost all patients with advanced pancreatic cancer will experience disease progression after first-line therapy. Nevertheless, many patients who retain good performance status after initial treatment remain good candidates for additional therapy. Historically, few studies have assessed second-line therapy, with most reports representing small phase II trials with variable findings; however, clinical research for second-line treatment has increased in the past decade, and several randomized controlled trials using different regimens have been published. The current literature shows varying results on treatment efficacy and tolerability. Thus, we reviewed the published data on the use of chemotherapy in the second-line setting for the treatment of advanced pancreatic cancer.
| S-EPMC6084072 | biostudies-literature
Project description:Background COVID-19 pandemic school shutdowns impacted child food security. Resilient school meal programs are imperative to cope and persist through shocks and stressors. Objective To explore unforeseen positive outcomes and determine best practices during the COVID-19 pandemic for child nutrition directors in Mississippi (MS), Louisiana (LA), and West Virginia (WV). Study Design, Setting, Participants A semi-structured focus group discussion guide was developed based on the resilience capacity model (RCM). Four focus group discussions with child nutrition directors (n = 16) from MS, LA, and WV were conducted to elicit directors’ perceptions of encouraging outcomes during the COVID-19 pandemic and best practices for building resilient school meal programs. Measurable Outcome/Analysis The discussion guide was tested for content validation by subject experts and face validation by testing the guide in one focus group discussion session. The primary researcher developed a codebook based on the conceptual RCM. Two researchers independently reviewed and coded transcripts to assess interrater reliability. Predominant themes were identified using an inductive and deductive content analysis approach. Results Encouraging outcomes included acknowledgment of school nutrition staff as essential workers and recognition of child nutrition programs as important for child food security. Best practices recommended by child nutrition directors include effective communication and networking among all personnel from policymakers to staff involved in food preparation and distribution, revision of standard operating procedures to include disaster/pandemic related mitigation strategies, taking initiatives to improve school meal provision process, and emergency management training for everyone involved in school meal provision process. Director recommendations included: in-class food distribution, increased food storage, preparation, and distribution equipment, and developing a best practices policy document for each state with a comprehensive plan for emergency management situations. Conclusions Future emergency school nutrition policies should encourage efficient communication, revision of existing standard operating procedures, and implement training for all school nutrition personnel. Funding Achieving Equity Investment Grant 2021 (University of Mississippi)
| S-EPMC9260006 | biostudies-literature