Ontology highlight
ABSTRACT:
SUBMITTER: Szumilas K
PROVIDER: S-EPMC7662687 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Szumilas Kamila K Szumilas Paweł P Słuczanowska-Głąbowska Sylwia S Zgutka Katarzyna K Pawlik Andrzej A
International journal of molecular sciences 20201104 21
Rheumatoid arthritis (RA) is a systemic chronic inflammatory autoimmune joint disease, characterized by progressive articular damage and joint dysfunction. One of the symptoms of this disease is persistent inflammatory infiltration of the synovial membrane, the principle site of inflammation in RA. In the affected conditions, the cells of the synovial membrane, fibroblast-like synoviocytes and macrophage-like synovial cells, produce enzymes degrading cartilage and underlining bone tissue, as wel ...[more]