Ontology highlight
ABSTRACT:
SUBMITTER: Ejtehadi HD
PROVIDER: S-EPMC1798125 | biostudies-literature | 2006 May
REPOSITORIES: biostudies-literature
Ejtehadi H D HD Freimanis G L GL Ali H A HA Bowman S S Alavi A A Axford J J Callaghan R R Nelson P N PN
Annals of the rheumatic diseases 20050928 5
<h4>Objective</h4>To examine whether human endogenous retrovirus K10 is associated with autoimmune rheumatic disease.<h4>Design</h4>A novel multiplex reverse transcription polymerase chain reaction (RT-PCR) system was developed to investigate HERV-K10 mRNA expression in patients with rheumatoid arthritis.<h4>Methods</h4>40 patients with rheumatoid arthritis, 17 with osteoarthritis, and 27 healthy individuals were recruited and total RNA was extracted from peripheral blood mononuclear cells (PBMC ...[more]