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Identifying potential biomarkers related to pre-term delivery by proteomic analysis of amniotic fluid.


ABSTRACT: We sought to identify biomarkers in the amniotic fluid (AF) and specific signaling pathways related to spontaneous preterm delivery (SPTD,

SUBMITTER: Hong S 

PROVIDER: S-EPMC7665029 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Identifying potential biomarkers related to pre-term delivery by proteomic analysis of amniotic fluid.

Hong Subeen S   Lee Ji Eun JE   Kim Yu Mi YM   Park Yehyon Y   Choi Ji-Woong JW   Park Kyo Hoon KH  

Scientific reports 20201112 1


We sought to identify biomarkers in the amniotic fluid (AF) and specific signaling pathways related to spontaneous preterm delivery (SPTD, < 34 weeks) in women with preterm labor (PTL) without intra-uterine infection/inflammation (IUI). This was a retrospective cohort study of a total of 139 PTL women with singleton gestation (24 + 0 to 32 + 6 weeks) who underwent amniocentesis and who displayed no evidence of IUI. A nested case-control was conducted using pooled AF samples (n = 20) analyzed via  ...[more]

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