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Antivirals With Adjunctive Corticosteroids Prevent Clinical Progression of Early Coronavirus 2019 Pneumonia: A Retrospective Cohort Study.


ABSTRACT: This is a retrospective cohort study of hospitalized adults with coronavirus disease 2019 (COVID-19). Fifty-seven patients received treatment alone, and 35 patients received treatment with adjunctive prednisolone. A combination of corticosteroids and antivirals was associated with lower risk of clinical progression and invasive mechanical ventilation or death in early COVID-19 pneumonia.

SUBMITTER: Ooi ST 

PROVIDER: S-EPMC7665708 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Antivirals With Adjunctive Corticosteroids Prevent Clinical Progression of Early Coronavirus 2019 Pneumonia: A Retrospective Cohort Study.

Ooi Say Tat ST   Parthasarathy Purnima P   Lin Yi Y   Nallakaruppan Valliammai D/O VD   Ng Shereen S   Tan Teck Choon TC   Low Serena S   Tang Terence T  

Open forum infectious diseases 20201014 11


This is a retrospective cohort study of hospitalized adults with coronavirus disease 2019 (COVID-19). Fifty-seven patients received treatment alone, and 35 patients received treatment with adjunctive prednisolone. A combination of corticosteroids and antivirals was associated with lower risk of clinical progression and invasive mechanical ventilation or death in early COVID-19 pneumonia. ...[more]

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