Ontology highlight
ABSTRACT:
SUBMITTER: Nunes A
PROVIDER: S-EPMC7665747 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Nunes Abraham A Trappenberg Thomas T Alda Martin M
PloS one 20201113 11
Normative modeling is an increasingly popular method for characterizing the ways in which clinical cohorts deviate from a reference population, with respect to one or more biological features. In this paper, we extend the normative modeling framework with an approach for measuring the amount of heterogeneity in a cohort. This heterogeneity measure is based on the Representational Rényi Heterogeneity method, which generalizes diversity measurement paradigms used across multiple scientific discipl ...[more]