Ontology highlight
ABSTRACT:
SUBMITTER: Aslanidou L
PROVIDER: S-EPMC7666086 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Aslanidou Lydia L Trachet Bram B Sasset Linda L Lovric Goran G Stergiopulos Nikolaos N Di Lorenzo Annarita A
Journal of vascular research 20200916 6
Aortic aneurysms and dissections are silent and lethal conditions, whose pathogenesis remains incompletely understood. Although angiotensin II (AngII)-infused ApoE-/- mice have been widely used to study aortic aneurysm and dissection, early morphofunctional alterations preceding the onset of these conditions remain unknown. The goal of this study was to unveil early morphofunctional changes underlying the onset of aneurysm and dissection. At 3 days post-AngII infusion, suprarenal abdominal aorta ...[more]