Ontology highlight
ABSTRACT:
SUBMITTER: Jimenez N
PROVIDER: S-EPMC7667288 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Jiménez Natalia N Reig Òscar Ò Montalbo Ruth R Milà-Guasch Maria M Nadal-Dieste Lluis L Castellano Giancarlo G Lozano Juan José JJ Victoria Iván I Font Albert A Rodriguez-Vida Alejo A Carles Joan J Suárez Cristina C Domènech Montserrat M Sala-González Núria N Fernández Pedro Luis PL Rodríguez-Carunchio Leonardo L Díaz Sherley S Prat Aleix A Marín-Aguilera Mercedes M Mellado Begoña B
Frontiers in oncology 20201102
The prostatic tumor cells plasticity is involved in resistance to hormone-therapy, allowing these cells to survive despite androgen receptor inhibition. However, its role in taxanes resistance has not been fully established. Gene expression of plasticity-related phenotypes such as epithelial-mesenchymal transition (EMT), stem cell-like and neuroendocrine (NE) phenotypes was studied <i>in vitro</i>, <i>in silico</i>, in circulating tumor cells (CTCs) (<i>N</i>=22) and in tumor samples (<i>N</i>=1 ...[more]