Ontology highlight
ABSTRACT:
SUBMITTER: Ballikaya S
PROVIDER: S-EPMC7667860 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Ballikaya Seda S Sadeghi Samar S Niebergall-Roth Elke E Nimtz Laura L Frindert Jens J Norrick Alexandra A Stemler Nicole N Bauer Nicole N Rosche Yvonne Y Kratzenberg Vanessa V Pieper Julia J Ficek Tina T Frank Markus H MH Ganss Christoph C Esterlechner Jasmina J Kluth Mark A MA
Stem cell research & therapy 20201116 1
<h4>Background</h4>Human dermal mesenchymal stromal cells (MSCs) expressing the ATP-binding cassette (ABC) efflux transporter ABCB5 represent an easily accessible MSC population that, based on preclinical and first-in-human data, holds significant promise to treat a broad spectrum of conditions associated not only with skin-related but also systemic inflammatory and/or degenerative processes.<h4>Methods</h4>We have developed a validated Good Manufacturing Practice-compliant expansion and manufac ...[more]