Ontology highlight
ABSTRACT:
SUBMITTER: Osan JK
PROVIDER: S-EPMC7668735 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Osan Jaspreet K JK Talukdar Sattya N SN Feldmann Friederike F DeMontigny Beth Ann BA Jerome Kailey K Bailey Kristina L KL Feldmann Heinz H Mehedi Masfique M
bioRxiv : the preprint server for biology 20201112
SARS-CoV-2 has become a major problem across the globe, with approximately 50 million cases and more than 1 million deaths and currently no approved treatment or vaccine. Chronic obstructive pulmonary disease (COPD) is one of the underlying conditions in adults of any age that place them at risk for developing severe illness associated with COVID-19. We established an airway epithelium model to study SARS-CoV-2 infection in healthy and COPD lung cells. We found that both the entry receptor ACE2 ...[more]