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Comprehensive flow cytometric reference intervals of leukocyte subsets from six study centers across Europe.


ABSTRACT: A group of European FOCIS Centers of Excellence adapted panels of the Human Immunophenotyping Consortium (HIPC) for whole blood analysis. Using four core panels [T/regulatory T cell/B/natural killer (T/Treg /B/NK) and myeloid cells] the main leukocyte populations were analyzed in a clinical-diagnostic setting in a harmonized manner across different platforms. As a first step, the consortium presents here the absolute and relative frequencies of the leukocyte subpopulations in the peripheral blood of more than 300 healthy volunteers across six different European centers.

SUBMITTER: Oras A 

PROVIDER: S-EPMC7670136 | biostudies-literature | 2020 Dec

REPOSITORIES: biostudies-literature

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Comprehensive flow cytometric reference intervals of leukocyte subsets from six study centers across Europe.

Oras A A   Quirant-Sanchez B B   Popadic D D   Thunberg S S   Winqvist O O   Heck S S   Cwikowski M M   Riemann D D   Seliger B B   Martinez Caceres E E   Uibo R R   Giese T T  

Clinical and experimental immunology 20200803 3


A group of European FOCIS Centers of Excellence adapted panels of the Human Immunophenotyping Consortium (HIPC) for whole blood analysis. Using four core panels [T/regulatory T cell/B/natural killer (T/T<sub>reg</sub> /B/NK) and myeloid cells] the main leukocyte populations were analyzed in a clinical-diagnostic setting in a harmonized manner across different platforms. As a first step, the consortium presents here the absolute and relative frequencies of the leukocyte subpopulations in the peri  ...[more]

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