Ontology highlight
ABSTRACT:
SUBMITTER: Van Brempt M
PROVIDER: S-EPMC7670410 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Van Brempt Maarten M Clauwaert Jim J Mey Friederike F Stock Michiel M Maertens Jo J Waegeman Willem W De Mey Marjan M
Nature communications 20201116 1
To engineer synthetic gene circuits, molecular building blocks are developed which can modulate gene expression without interference, mutually or with the host's cell machinery. As the complexity of gene circuits increases, automated design tools and tailored building blocks to ensure perfect tuning of all components in the network are required. Despite the efforts to develop prediction tools that allow forward engineering of promoter transcription initiation frequency (TIF), such a tool is stil ...[more]