Ontology highlight
ABSTRACT:
SUBMITTER: Charrout M
PROVIDER: S-EPMC7671373 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
Charrout Mohammed M Reinders Marcel J T MJT Mahfouz Ahmed A
NAR genomics and bioinformatics 20200722 3
Advances in single-cell RNA sequencing over the past decade has shifted the discussion of cell identity toward the transcriptional state of the cell. While the incredible resolution provided by single-cell RNA sequencing has led to great advances in unraveling tissue heterogeneity and inferring cell differentiation dynamics, it raises the question of which sources of variation are important for determining cellular identity. Here we show that confounding biological sources of variation, most not ...[more]