Ontology highlight
ABSTRACT:
SUBMITTER: Shrivastava-Ranjan P
PROVIDER: S-EPMC7671970 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Frontiers in cellular and infection microbiology 20201104
Andes virus (ANDV) and Sin Nombre virus (SNV), highly pathogenic hantaviruses, cause hantavirus pulmonary syndrome in the Americas. Currently no therapeutics are approved for use against these infections. Griffithsin (GRFT) is a high-mannose oligosaccharide-binding lectin currently being evaluated in phase I clinical trials as a topical microbicide for the prevention of human immunodeficiency virus (HIV-1) infection (ClinicalTrials.gov Identifiers: NCT04032717, NCT02875119) and has shown broad-s ...[more]