Ontology highlight
ABSTRACT:
SUBMITTER: Bozovic O
PROVIDER: S-EPMC7673989 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Bozovic Olga O Jankovic Brankica B Hamm Peter P
Nature communications 20201117 1
Allosteric regulation is an innate control in most metabolic and signalling cascades that enables living organisms to adapt to the changing environment by tuning the affinity and regulating the activity of target proteins. For a microscopic understanding of this process, a protein system has been designed in such a way that allosteric communication between the binding and allosteric site can be observed in both directions. To that end, an azobenzene-derived photoswitch has been linked to the α3- ...[more]