Ontology highlight
ABSTRACT:
SUBMITTER: Sun Y
PROVIDER: S-EPMC7675574 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Sun Yiwen Y Liu Chuan C Tang Wenzhu W Zhang Dawei D
ACS omega 20201102 45
Guanosine monophosphate, the precursor for riboflavin biosynthesis, can be converted to or generated from other purine compounds in purine metabolic networks. In this study, genes in these networks were manipulated in a riboflavin producer, <i>Bacillus subtilis</i> R, to test their contribution to riboflavin biosynthesis. Knocking out adenine phosphoribosyltransferase (<i>apt</i>), xanthine phosphoribosyltransferase (<i>xpt</i>), and adenine deaminase (<i>adeC</i>) increased the riboflavin produ ...[more]