Ontology highlight
ABSTRACT:
SUBMITTER: Iida M
PROVIDER: S-EPMC7681064 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Iida Machiko M Tazaki Akira A Yajima Ichiro I Ohgami Nobutaka N Taguchi Nobuhiko N Goto Yuji Y Kumasaka Mayuko Y MY Prévost-Blondel Armelle A Kono Michihiro M Akiyama Masashi M Takahashi Masahide M Kato Masashi M
Aging cell 20201107 11
Hair graying is a representative sign of aging in animals and humans. However, the mechanism for hair graying with aging remains largely unknown. In this study, we found that the microscopic appearance of hair follicles without melanocyte stem cells (MSCs) and descendant melanocytes as well as macroscopic appearances of hair graying in RET-transgenic mice carrying RET oncogene (RET-mice) are in accordance with previously reported results for hair graying in humans. Therefore, RET-mice could be a ...[more]