Ontology highlight
ABSTRACT:
SUBMITTER: Trites MJ
PROVIDER: S-EPMC7683526 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Trites Michael J MJ Febbraio Maria M Clugston Robin D RD
Scientific reports 20201123 1
Fatty acid translocase (CD36) is a scavenger receptor with multiple ligands and diverse physiological actions. We recently reported that alcohol-induced hepatic retinoid mobilization is impaired in Cd36<sup>-/-</sup> mice, leading us to hypothesize that CD36 has a novel role in hepatic vitamin A mobilization. Given the central role of the liver in systemic vitamin A homeostasis we also postulated that absence of CD36 would affect whole-body vitamin A homeostasis. We tested this hypothesis in agi ...[more]