Ontology highlight
ABSTRACT:
SUBMITTER: Zhu W
PROVIDER: S-EPMC7684788 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Zhu Wei W Chen Catherine Z CZ Gorshkov Kirill K Xu Miao M Lo Donald C DC Zheng Wei W
SLAS discovery : advancing life sciences R & D 20200713 10
COVID-19 respiratory disease caused by the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has rapidly become a global health issue since it emerged in December 2019. While great global efforts are underway to develop vaccines and to discover or repurpose therapeutic agents for this disease, as of this writing only the nucleoside drug remdesivir has been approved under Emergency Use Authorization to treat COVID-19. The RNA-dependent RNA polymerase (RdRP), a viral enzyme for viral RN ...[more]