Ontology highlight
ABSTRACT:
SUBMITTER: Fignani D
PROVIDER: S-EPMC7691425 | biostudies-literature | 2020
REPOSITORIES: biostudies-literature
Fignani Daniela D Licata Giada G Brusco Noemi N Nigi Laura L Grieco Giuseppina E GE Marselli Lorella L Overbergh Lut L Gysemans Conny C Colli Maikel L ML Marchetti Piero P Mathieu Chantal C Eizirik Decio L DL Sebastiani Guido G Dotta Francesco F
Frontiers in endocrinology 20201113
Increasing evidence demonstrated that the expression of Angiotensin I-Converting Enzyme type 2 (ACE2) is a necessary step for SARS-CoV-2 infection permissiveness. In light of the recent data highlighting an association between COVID-19 and diabetes, a detailed analysis aimed at evaluating ACE2 expression pattern distribution in human pancreas is still lacking. Here, we took advantage of INNODIA network EUnPOD biobank collection to thoroughly analyze ACE2, both at mRNA and protein level, in multi ...[more]