Ontology highlight
ABSTRACT:
SUBMITTER: Xie C
PROVIDER: S-EPMC7692862 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Xie Caroline C Prasad Asheeta A AA
Microorganisms 20201027 11
Parkinson's disease (PD) is a neurological disorder with motor dysfunction and a number of psychiatric symptoms. Symptoms such as anxiety and cognitive deficits emerge prior to motor symptoms and persist over time. There are limited treatments targeting PD psychiatric symptoms. Emerging studies reveal that the gut microbe is altered in PD patients. Here we assessed the effect of a probiotic treatment in a rat model of PD. We used the neurotoxin (6-hydroxydopamine, 6-OHDA) in a preclinical PD mod ...[more]