Ontology highlight
ABSTRACT:
SUBMITTER: Fratelli C
PROVIDER: S-EPMC7692865 | biostudies-literature | 2020 Oct
REPOSITORIES: biostudies-literature
Fratelli Caroline C Siqueira Jhon J Silva Calliandra C Ferreira Eduardo E Silva Izabel I
Genes 20201026 11
Major Depressive Disorder (MDD) is a disease that involves biological, psychological, and social interactions. Studies have shown the importance of genetics contribution to MDD development. The SCL6A4 protein (5HTTLPR) functions transporting serotonin, a neurotransmitter linked to mood and emotion, to the synaptic cleft. Hence, this study seeks, through a literature review, a better comprehension of the 5HTTLPR genetic variant association with MDD. For this purpose, a search was performed on the ...[more]