Proteomics

Dataset Information

0

ITRAQ paroxetine response in major depressive disorder


ABSTRACT: Identify blood proteins relevant to paroxetine response in patients with major depressive disorder (MDD)

INSTRUMENT(S): Q Exactive

ORGANISM(S): Homo Sapiens (human)

TISSUE(S): Blood Cell, Blood

DISEASE(S): Major Depressive Disorder

SUBMITTER: Chin-Chuen Lin  

LAB HEAD: Jia-Wei Chen

PROVIDER: PXD028947 | Pride | 2022-05-20

REPOSITORIES: Pride

Dataset's files

Source:
Action DRS
Lith-PBMC_F1_F0.msf Msf
Lith-PBMC_F1_F0.mzML Mzml
Lith-PBMC_F1_F0.mzid.gz Mzid
Lith-PBMC_F1_F0.raw Raw
Lith-PBMC_F2.raw Raw
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Publications

Isobaric Tags for Relative and Absolute Quantitation Identification of Blood Proteins Relevant to Paroxetine Response in Patients With Major Depressive Disorder.

Lin Chin-Chuen CC   Su Hung H   Shiea Jentaie J   Huang Tiao-Lai TL  

Frontiers in psychiatry 20220418


<h4>Objectives</h4>Isobaric tags for relative and absolute quantitation (iTRAQ) is a proteomic investigation that could be utilized for rapid identification and quantification of proteins, which we would use to identify differentially expressed proteins in treatment responsive patients with major depressive disorder (MDD).<h4>Methods</h4>Six treatment responsive patients of MDD were recruited, and their peripheral blood mononuclear cell (PBMC) were collected before and after 4 weeks of paroxetin  ...[more]

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