Ontology highlight
ABSTRACT:
SUBMITTER: Ng TP
PROVIDER: S-EPMC7695406 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Ng Tze Pin TP Lu Yanxia Y Tan Crystal Tze Ying CTY Gao Qi Q Gwee Xinyi X Fulop Tamas T Larbi Anis A
Aging 20201106 21
Human evidence for the role of continuous antigenic stimulation from persistent latent infections in frailty is limited. We conducted a nested case-control study (99 deceased and 43 survivors) of participants aged 55 and above in a longitudinal ageing cohort followed up from 2003 to 2017. Using blood samples and baseline data collected in 2003-2004, we examined the association of pathogenic load (PL) count of seropositivity to 10 microbes (viruses, bacteria and mycoplasma) with cumulated deficit ...[more]