Ontology highlight
ABSTRACT:
SUBMITTER: Razazi K
PROVIDER: S-EPMC7699579 | biostudies-literature | 2020 Nov
REPOSITORIES: biostudies-literature
Razazi Keyvan K Gendreau Ségolène S Cuquemelle Elise E Khellaf Mehdi M Guillaud Constance C Godeau Bertrand B Melica Giovanna G Moutereau Stéphane S Gomart Camille C Fourati Slim S De Prost Nicolas N Carteaux Guillaume G Brun-Buisson Christian C Bartolucci Pablo P Habibi Anoosha A Mekontso Dessap Armand A
Journal of clinical medicine 20201119 11
Acute chest syndrome (ACS) is a major complication of sickle-cell disease. Bacterial infection is one cause of ACS, so current guidelines recommend the routine use of antibiotics. We performed a prospective before-after study in medical wards and an intensive-care unit (ICU). During the control phase, clinicians were blinded to procalcitonin concentration results. We built an algorithm using the obtained measurements to hasten antibiotic cessation after three days of treatment if bacterial infec ...[more]