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Alcohol-free hand sanitizer and other quaternary ammonium disinfectants quickly and effectively inactivate SARS-CoV-2.

ABSTRACT: SARS-CoV-2 is the virus responsible for the current global pandemic, COVID-19. Because this virus is novel, little is known about its sensitivity to disinfection. In this study, we performed suspension tests against SARS-CoV-2 using three commercially available quaternary ammonium compound (Quat) disinfectants and one laboratory-made 0.2% benzalkonium chloride solution. Three of the four formulations completely inactivated the virus within 15 seconds of contact, even in the presence of a soil load or when diluted in hard water. We conclude that Quats rapidly inactivate SARS-CoV-2, making them potentially useful for controlling SARS-CoV-2 spread in hospitals and the community.

SUBMITTER: Ogilvie BH

PROVIDER: S-EPMC7700010 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Alcohol-free hand sanitizer and other quaternary ammonium disinfectants quickly and effectively inactivate SARS-CoV-2.

Ogilvie B H BH Solis-Leal A A Lopez J B JB Poole B D BD Robison R A RA Berges B K BK

The Journal of hospital infection 20201128

<h4>Background</h4>SARS-CoV-2 is the virus responsible for the current global pandemic, COVID-19. Because this virus is novel, little is known about its sensitivity to disinfection.<h4>Methods</h4>We performed suspension tests against SARS-CoV-2 using three commercially available quaternary ammonium compound (Quat) disinfectants and one laboratory-made 0.2% benzalkonium chloride solution.<h4>Findings</h4>Three of the four formulations completely inactivated the virus within 15 s of contact, even ...[more]

PMID: 33259880

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