Real-world long-term outcomes in individuals at clinical risk for psychosis: The case for extending duration of care.

ABSTRACT:

Background

Most services for individuals at Clinical High Risk for Psychosis (CHR-P) provide short-term clinical care. This study determines the real-world and long-term clinical outcomes beyond transition to psychosis in a large cohort of CHR-P individuals.

Method

Retrospective RECORD-compliant real-world Electronic Health Records (EHR) cohort study in secondary mental health care (the South London and the Maudsley -SLaM- NHS Foundation Trust). All CHR-P patients accessing the CHR-P service at SLaM in the period 2001-2018 were included. Main outcomes were long-term cumulative risk of first: (i) developing an ICD-10 psychotic disorder (primary outcome), receiving a treatment with (iia) antipsychotic medication, (iib) benzodiazepines, (iic) other psychotropic medications, (ii

SUBMITTER: Fusar-Poli P 

PROVIDER: S-EPMC7700893 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature