Ontology highlight
ABSTRACT:
SUBMITTER: Van der Meeren L
PROVIDER: S-EPMC7702191 | biostudies-literature | 2020 Dec
REPOSITORIES: biostudies-literature
Van der Meeren Louis L Verduijn Joost J Krysko Dmitri V DV Skirtach André G AG
iScience 20201117 12
Regulated cell death (RCD) has a fundamental role in development, pathology, and tissue homeostasis. In order to understand the RCD mechanisms, it is essential to follow these processes in real time. Here, atomic force microscopy (AFM) is applied to morphologically and mechanically characterize four RCD modalities (intrinsic and extrinsic apoptosis, necroptosis, and ferroptosis) in murine tumor cell lines. The nano-topographical analysis revealed a distinct surface morphology in case of necropto ...[more]