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Preoperative intravenous rehydration for patients with pheochromocytomas and paragangliomas: is it necessary? A propensity score matching analysis.


ABSTRACT:

Background

Preoperative intravenous rehydration for patients with pheochromocytomas and paragangliomas (PPGLs) is widely used in many medical centers, but its usefulness has not been well evaluated. The objective of this study was to compare the perioperative hemodynamics and early outcome between patients who received preoperative intravenous rehydration and those without for resection of PPGLs.

Methods

In this retrospective propensity score-matched cohort study, the data of patients who underwent surgery for PPGLs were collected. Patients were divided into two groups depending on whether they received or did not receive intravenous rehydration preoperatively. The primary endpoint was intraoperative hypotension, described as the cumulative time of mean arterial pressure?ResultsAmong 231 enrolled patients, 113 patients received intravenous rehydration of ?2000?ml daily for ?2?days before surgery and 118 patients who did not have any intravenous rehydration before surgery. After propensity score matching, 85 patients remained in each group. The median cumulative time of mean arterial pressure?ConclusionsFor patients with PPGLs, preoperative intravenous rehydration failed to optimize perioperative hemodynamics or improve early outcome.

SUBMITTER: Kong H 

PROVIDER: S-EPMC7702709 | biostudies-literature | 2020 Nov

REPOSITORIES: biostudies-literature

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Publications

Preoperative intravenous rehydration for patients with pheochromocytomas and paragangliomas: is it necessary? A propensity score matching analysis.

Kong Hao H   Yang Jiao-Nan JN   Tian Jie J   Li Nan N   Zhang Yu-Xiu YX   Ye Peng-Cheng PC   Li Xue-Ying XY   Zhang Zheng Z  

BMC anesthesiology 20201130 1


<h4>Background</h4>Preoperative intravenous rehydration for patients with pheochromocytomas and paragangliomas (PPGLs) is widely used in many medical centers, but its usefulness has not been well evaluated. The objective of this study was to compare the perioperative hemodynamics and early outcome between patients who received preoperative intravenous rehydration and those without for resection of PPGLs.<h4>Methods</h4>In this retrospective propensity score-matched cohort study, the data of pati  ...[more]

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